REP1 Polyclonal Antibody

Catalog No.:AB0123-200

Price / Unit: EUR 320.00

Source: Goat

Quantity/unit size: 800 µg

Description: REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.

Alternative names:
CHM, choroideremia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.

Form: Polyclonal antibody supplied as a 200 µl (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.

Specificity: Detects endogenous Rep1 and in transfected cells by Western blot.

Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.

Usage: Western blot                          1:500-1:2,000
Immunofluorescence                                ND
Immunohistochemistry (paraffin)              ND
Immunohistochemistry (frozen)                ND

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ ND ND ND
rat +++ ND ND ND
mouse +++ ND ND ND
canine +++ ND ND ND
monkey +++ ND ND ND

Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.

References




For research use only, not for diagnostic use