Rab3 Pan Polyclonal Antibody

Catalog No.:AB10032-200

Price / Unit: EUR 320.00

Source: Goat

Quantity/unit size: 600 µg

Description: Goat polyclonal antibody to mouse Rab3. Rab3 belongs to the small GTPase superfamily, Rab family. Rab3 is involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

Alternative names: RAB3A, RAB3B, RAB3C, RAB3D, RAS-associated protein RAB3A, ras-related protein Rab-3B, RAS-associated protein RAB3C, RAS-associated protein RAB3D, ras-related protein Rab-3A, ras-related protein Rab-3B, ras-related protein Rab-3C, ras-related protein Rab-3D antibody.

Form: Polyclonal antibody supplied as a 200 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptides derived from within residues 110 aa to the C-terminus of mouse Rab3a produced in E. coli.

Specificity: Detects total Rab3 protein in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab3a, GFP-Rab3b and GFP-Rab3c cds by Western blot.

Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.

Usage: Western blot                            1:250-1:1,000
Immunofluorescence                              1:50-1:250
Immunohistochemistry (paraffin)          1:250-1:1,500
Immunohistochemistry (froz                 1:250-1:1,500

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ +++ +++ +++
rat +++ +++ +++ +++
mouse +++ +++ +++ +++
canine +++ +++ +++ +++
monkey +++ +++ +++ +++

Storage: Store at -20 C for long term storage. Store at 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.

References

1. Encarnação M, Espada L, Escrevente C, et al. J Cell Biol. 2016 Jun 20. PMID: 27325790



For research use only, not for diagnostic use