Rab2 Pan Polyclonal Antibody

Catalog No.:AB10021-200

Price / Unit: EUR 300.00

Source: Goat

Quantity/unit size: 400 µg

Description: RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A has been shown to interact with GOLGA2.

Alternative names: Ras-related protein Rab-2A, Ras-related protein Rab-2B antibody.

Form: Polyclonal antibody supplied as a 200 µl (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.

Specificity: Detects total levels of Rab2 protein in transfected cells with GFP-Rab2a and GFP-Rab2b by Western blot.

Reactivity: Reacts against human, rat, mouse, monkey and canine proteins.

Usage: Western blot                           1:250-1:2,000
Immunofluorescence                                    ND
Immunohistochemistry (paraffin)                  ND
Immunohistochemistry (frozen)                    ND

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ ND ND ND
rat +++ ND ND ND
mouse +++ ND ND ND
canine +++ ND ND ND
monkey +++ ND ND ND

Storage: Store at -20 C for long term storage. Store at 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.

References



For research use only, not for diagnostic use