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N-Cadherin Polyclonal Antibody

Catalog No.:AB0071-200

Price / Unit: EUR 300.00

Source: Goat

Quantity/unit size: 600 µg

Description: Goat polyclonal to CDH2. CDH2 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one transmembrane domain, and a and a highly conserved intracellular domain. It has been shown to play an essential role in normal neuronal development, which is implicated in an array of processes including neuronal differentiation, migration, axon growth and fasciculation.

Alternative names: cadherin 2, cadherin-2, CD325, CDHN, CDw325, CDH2, NCAD, N-cadherin, N-cadherin 1, neural cadherin, neural-cadherin, neural cadherin (NCAD) antibody.

Form: Polyclonal antibody supplied as a 200 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptide derived from within residues 850 aa to C-terminus of human CDH2 produced in E. coli.

Specificity: Detects endogenous levels of total N-cadherin protein by Western blot in the whole cell lysates (COS-7 and MDCK).

Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.

Usage: Western blot                         1:500-1:2,000
Immunofluorescence                           1:25-1:250
Immunohistochemistry (paraffin)                ND
Immunohistochemistry (frozen)                  ND

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ +++ ND ND
rat +++ +++ ND ND
mouse +++ +++ ND ND
monkey +++ +++ ND ND
canine +++ +++ ND ND

Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.

References




For research use only, not for diagnostic use