Lamin A/C Polyclonal Antibody

Catalog No.:AB0093-100

Price / Unit: EUR 320.00

Source: Goat

Quantity/unit size: 300 µg

Description: Goat polyclonal to LMNA (Lamin A/C) - nucleus marker. The Lamin family of proteins make up the matrix of proteins located next to the inner nuclear membrane. During mitosis, the lamina matrix is reversibly disassembled as the Lamin proteins are phosphorylated. These proteins are thought to be involved in chromatin structure, nuclear stability and gene expression.

Alternative names: CDDC, CDCD1, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2 HGPS, IDC, LDP1, LFP, LGMD1B, LMNC, LMN1, LMNL1, PRO1 antibody.

Form: Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptide within residues 620 aa to C-term of human LMNA produced in E. coli.

Specificity: Detects a band of 65-70 kDa by Western blot in whole cell lysates.

Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.

Usage: Western blot                         1:500-1:5,000
Immunofluorescence                               ND
Immunohistochemistry (paraffin)             ND
Immunohistochemistry (frozen)               ND

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ ND ND ND
rat +++ ND ND ND
mouse +++ ND ND ND
canine +++ ND ND ND
monkey +++ ND ND ND

Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.

References




For research use only, not for diagnostic use