Catalog No.:AB0088-200
Price / Unit: EUR 320.00
Source: Goat
Quantity/unit size: 600 µg
Description: Goat polyclonal antibody to ERBB2. This protein ia a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases containing a single transmembrane domain and has an approximate molecular weight of 185 kD. ERBB2 contains no ligand binding domain and interacts with other EGF receptor family members to form a heterodimer, stabilize ligand binding, and enhance kinase-mediated downstream signaling. It has been shown to be involved in embryonic development and cancer progression.
Alternative names: CD340, erb-b2 receptor tyrosine kinase 2, HER2, HER-2, HER-2/neu, MLN 19, NEU, NGL and TKR1 antibody.
Form: Polyclonal antibody supplied as a 200 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Immunogen: Recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.
Specificity: Detects endogenous levels of ERBB2 by Western blot.
Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.
Usage: Western blot 1:500-1:5,000
Immunofluorescence ND
Immunohistochemistry (paraffin) ND
Immunohistochemistry (frozen) ND
Reactivity chart
Sample | Western Blot | Immuno-fluorescence | Immuno-Histochemistry (p) | Immuno-Histochemistry (f) | human | +++ | ND | ND | ND | rat | +++ | ND | ND | ND | mouse | +++ | ND | ND | ND | canine | +++ | ND | ND | ND | monkey | +++ | ND | ND | ND |
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Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
Special instructions: Avoid freeze/thaw cycles.

References
For research use only, not for diagnostic use