Catalog No.:AB0091-200
Price / Unit: EUR 300.00
Source: Goat
Quantity/unit size: 600 µg
Description: Goat polyclonal antibody to CD4. CD4 is a member of the immunoglobulin superfamily, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and a receptor for the human immunodeficiency virus. This protein is expressed not only on the surface of T helper cells and regulatory T cells but also on monocytes, macrophages and dendritic cells. It functions to initiate or amplify the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Alternative names: CD4mut, CD4 antigen (p55), CD4 Receptor , T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.
Form: Polyclonal antibody supplied as a 200 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Immunogen: Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.
Specificity: Using spleen lysate detects a 52 kDa band by Western blot.
Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.
Usage: Western blot 1:500-1:2,000
Immunofluorescence ND
Immunohistochemistry (paraffin) ND
Immunohistochemistry (frozen) ND
Reactivity chart
Sample | Western Blot | Immuno-fluorescence | Immuno-Histochemistry (p) | Immuno-Histochemistry (f) | human | +++ | ND | ND | ND | rat | +++ | ND | ND | ND | mouse | +++ | ND | ND | ND | canine | +++ | ND | ND | ND | monkey | +++ | ND | ND | ND |
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Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
Special instructions: Avoid freeze/thaw cycles.

References
1. Helsby MA, Leader PM, Fenn JR, et al. BMC Cell Biol. 2014 Feb. PMID:24528853
For research use only, not for diagnostic use