Calnexin Polyclonal Antibody

Catalog No.:AB0041-200

Price / Unit: EUR 320.00

Source: Goat

Quantity/unit size: 400 µg

Description: Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Alternative names: Calnexin, CALX, CNX, FLJ26570,  histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.

Form: Polyclonal antibody supplied as a 200 µl (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Immunogen: Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.

Specificity: Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118,  rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates.

Reactivity: Reacts against human, rat, mouse, monkey and canine proteins.

Usage: Western blot                              1:500-1:5,000
Immunofluorescence                               1:50-1:500
Immunohistochemistry (paraffin)           1:200-1:1,000
Immunohistochemistry (frozen)             1:200-1:1,000

Reactivity chart

Sample Western Blot Immuno-fluorescence Immuno-Histochemistry (p) Immuno-Histochemistry (f)
human +++ +++ +++ +++
rat +++ +++ +++ +++
mouse +++ +++ +++ +++
canine +++ +++ +++ +++
monkey +++ +++ +++ +++

Storage: Store at -20 C for long term storage and 2-8 C for up to one month.

Special instructions: Avoid freeze/thaw cycles.


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12. Neves MMM, MSc Thesis, University of Coimbra, Portugal 2015
13. Ferreira RRS, MSc Thesis, Coimbra University 2015
14. Paiva RA, MSc Thesis, Coimbra University 2015
15. Samtleben S, PhD Thesis, Universität Würzburg 2014
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17. Marques, CIR, MSc Thesis, Coimbra University 2013

For research use only, not for diagnostic use

*This antibody is identical to AB4100.